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Posted by: PurpleHeart on 2010-06-18, 04:54:06
Copy pasted from Goodman Gilman pharmacology book These are the variables that contributes to addiction: Agent (drug) Availability Cost Purity/ potency Mode of administration Chewing (absorption via oral mucous membranes) Gastrointestinal Intranasal Subcutaneous and intramuscular Intravenous Inhalation Speed of onset and termination of effects (pharmacokinetics: combination of agent and host) Host (user) Heredity Innate tolerance Speed of developing acquired tolerance Likelihood of experiencing intoxication as pleasure Metabolism of the drug (nicotine and alcohol data already available) Psychiatric symptoms Prior experiences/ expectations Propensity for risk-taking behavior Environment Social setting Community attitudes Peer influence, role models Availability of other reinforcers (sources of pleasure or recreation) Employment or educational opportunities Conditioned stimuli: Environmental cues become associated with drugs after repeated use in the same environment As you see, it consists of three big parts, the agent, the host, and the environment. Well you can say, it's not always the role models, it could be the agent, or genetic, etc |